LncRNA MIAT: Myocardial infarction associated and more

被引：166

作者：

Liao, Jiangquan ^{[1
,2
]}

He, Qingyong ^{[1
]}

Li, Min ^{[1
,2
]}

Chen, Yinfeng ^{[1
,2
]}

Liu, Yongmei ^{[1
]}

Wang, Jie ^{[1
]}

机构：

[1] China Acad Chinese Med Sci, Guanganmen Hosp, 5 Beixiange St, Beijing 100053, Peoples R China

[2] Beijing Univ Chinese Med, Grad Sch, 11 Beisanhuan East Rd, Beijing 100029, Peoples R China

来源：

GENE | 2016年 / 578卷 / 02期

关键词：

Long noncoding RNA; MIAT; GOMAFU; LONG NONCODING RNAS; HUMAN GENOME; HUMAN QKI; SCHIZOPHRENIA; GENE; IDENTIFICATION; EXPRESSION; VARIANTS; RISK; POLYMORPHISMS;

D O I：

10.1016/j.gene.2015.12.032

中图分类号：

Q3 [遗传学];

学科分类号：

071007 [遗传学];

摘要：

Non-coding RNAs are emerging as regulatory RNAs that participate in the regulation of gene expression and play vital roles in various biological and pathological processes. Long non-coding (lncRNA) is a novel class of non coding RNAs that regulates gene expression by binding to chromatin regulators and interfering RNAs to affect cellular response. Myocardial infarction associated transcript (MIAT) is identified as lncRNAs, which is involved in various diseases, pathological and physiological processes, such as myocardial infarction, diabetic retinopathy, paranoid schizophrenia, microvascular dysfunction and formation of nuclear bodies, and neurogenic commitment. Here we review the growing understanding and potential utilization of MIAT. (C) 2015 Published by Elsevier B.V.

引用

页码：158 / 161

页数：4

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