Phylogenetic and functional classification of ATP-binding cassette (ABC) systems
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作者:
Bouige, P
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Inst Pasteur, CNRS, URA 1444, Unite Programmat Mol & Toxicol Genet, F-75724 Paris 15, FranceInst Pasteur, CNRS, URA 1444, Unite Programmat Mol & Toxicol Genet, F-75724 Paris 15, France
Bouige, P
[1
]
Laurent, D
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Inst Pasteur, CNRS, URA 1444, Unite Programmat Mol & Toxicol Genet, F-75724 Paris 15, FranceInst Pasteur, CNRS, URA 1444, Unite Programmat Mol & Toxicol Genet, F-75724 Paris 15, France
Laurent, D
[1
]
Piloyan, L
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Inst Pasteur, CNRS, URA 1444, Unite Programmat Mol & Toxicol Genet, F-75724 Paris 15, FranceInst Pasteur, CNRS, URA 1444, Unite Programmat Mol & Toxicol Genet, F-75724 Paris 15, France
Piloyan, L
[1
]
Dassa, E
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Inst Pasteur, CNRS, URA 1444, Unite Programmat Mol & Toxicol Genet, F-75724 Paris 15, FranceInst Pasteur, CNRS, URA 1444, Unite Programmat Mol & Toxicol Genet, F-75724 Paris 15, France
Dassa, E
[1
]
机构:
[1] Inst Pasteur, CNRS, URA 1444, Unite Programmat Mol & Toxicol Genet, F-75724 Paris 15, France
ATP binding cassette (ABC) systems constitute one of the most abundant superfamilies of proteins. They are involved in the transport of a wide variety of substances, but also in many cellular processes and in their regulation. In this paper, we made a comparative analysis of the properties of ABC systems and we provide a phylogenetic and functional classification. This analysis will be helpful to accurately annotate ABC systems discovered during the sequencing of the genome of living organisms and to identify the partners of the ABC ATPases.