Phylogenetic and functional classification of ATP-binding cassette (ABC) systems

被引:92
作者
Bouige, P [1 ]
Laurent, D [1 ]
Piloyan, L [1 ]
Dassa, E [1 ]
机构
[1] Inst Pasteur, CNRS, URA 1444, Unite Programmat Mol & Toxicol Genet, F-75724 Paris 15, France
关键词
D O I
10.2174/1389203023380486
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
ATP binding cassette (ABC) systems constitute one of the most abundant superfamilies of proteins. They are involved in the transport of a wide variety of substances, but also in many cellular processes and in their regulation. In this paper, we made a comparative analysis of the properties of ABC systems and we provide a phylogenetic and functional classification. This analysis will be helpful to accurately annotate ABC systems discovered during the sequencing of the genome of living organisms and to identify the partners of the ABC ATPases.
引用
收藏
页码:541 / 559
页数:19
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