Chromosome dynamics: New light on Aurora B kinase function

被引：71

作者：

Shannon, KB ^{[1
]}

Salmon, ED ^{[1
]}

机构：

[1] Univ N Carolina, Dept Biol, Chapel Hill, NC 27599 USA

来源：

CURRENT BIOLOGY | 2002年 / 12卷 / 13期

关键词：

D O I：

10.1016/S0960-9822(02)00945-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Aurora B family kinases play an essential role in chromosome segregation and cytokinesis. Recent work suggests that the kinase activity is required for bipolar chromosome orientation, kinetochore assembly, spindle checkpoint and microtubule dynamics. Aurora B also has additional functions in chromosome condensation and cohesion.

引用

页码：R458 / R460

页数：3

共 17 条

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