Administration of Brincidofovir and Convalescent Plasma in a Patient With Ebola Virus Disease

被引：68

作者：

Florescu, Diana F. ^{[1
,2
]}

Kalil, Andre C. ^{[1
]}

Hewlett, Angela L. ^{[1
]}

Schuh, Amy J. ^{[3
,4
]}

Stroher, Ute ^{[3
,4
]}

Uyeki, Timothy M. ^{[5
]}

Smith, Philip W. ^{[1
]}

机构：

[1] Univ Nebraska, Med Ctr, Div Infect Dis, Omaha, NE 68182 USA

[2] Univ Nebraska, Med Ctr, Transplant Surg Program, Omaha, NE 68182 USA

[3] Ctr Dis Control & Prevent, Viral Special Pathogens Branch, Div High Consequence Pathogens, Atlanta, GA USA

[4] Ctr Dis Control & Prevent, Pathol Natl Ctr Emerging & Zoonot, Atlanta, GA USA

[5] Ctr Dis Control & Prevent, Influenza Div, Natl Ctr Immunizat & Resp Dis, Atlanta, GA USA

来源：

CLINICAL INFECTIOUS DISEASES | 2015年 / 61卷 / 06期

关键词：

Ebola; investigational therapies; trials; HUMORAL IMMUNE-RESPONSE; HEMORRHAGIC-FEVER; CMX001; SUDAN; INFECTIONS; OUTBREAK; GULU;

D O I：

10.1093/cid/civ395

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

From 2014 to May 2015, >26 000 Ebola virus disease (EVD) cases were reported from West Africa. We present a patient with EVD who received brincidofovir and convalescent plasma. The relative contributions of supportive care, investigational therapies, and patient's immune-response on survival could not be determined. Randomized trials are needed.

引用

页码：969 / 973

页数：5

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