Quantitative comparison of five SERS substrates: Sensitivity and limit of detection

被引：143

作者：

Norrod, KL ^{[1
]}

Sudnik, LM ^{[1
]}

Rousell, D ^{[1
]}

Rowlen, KL ^{[1
]}

机构：

[1] UNIV COLORADO,DEPT CHEM & BIOCHEM,BOULDER,CO 80309

来源：

APPLIED SPECTROSCOPY | 1997年 / 51卷 / 07期

关键词：

surface-enhanced Raman spectroscopy; silver; substrates; sensitivity; limit of detection;

D O I：

10.1366/0003702971941377

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

Five surface-enhanced Raman scattering (SERS) substrates were quantitatively compared for ease of preparation, sensitivity, limit of detection (LOD), reproducibility, and stability. Specifically, vapor-deposited Ag films, electrochemically roughened Ag electrodes, nitric acid-etched Ag foil, Tollens-produced Ag films, and photoreduced Ag films on TiO2 were examined. Of these substrates, post-deposition-annealed Ag films exhibited the greatest sensitivity and lowest LOD, with 152 +/- 1 counts per femtomole and an LOD of 0.36 +/- 0.02 femtomoles of trans-1,2-bis(4-pyridyl)ethene (BPE). The substrate demonstrating the poorest sensitivity and highest LOD was Ag deposited from the Tollens reaction, with 0.38 +/- 0.01 counts per femtomole and an LOD of 270 +/- 20 femtomoles of BPE. The easiest substrate to prepare, nitric acid-etched Ag foils, exhibited a sensitivity of 0.485 +/- 0.008 counts per femtomole and an LOD of 200 +/- 10 femtomoles of BPE.

引用

页码：994 / 1001

页数：8

共 29 条

[11] APPROACH TO SINGLE-MOLECULE DETECTION USING SURFACE-ENHANCED RESONANCE RAMAN-SCATTERING (SERRS) - A STUDY USING RHODAMINE 6G ON COLLOIDAL SILVER [J].