Movement-related cortical activation in familial Parkinson disease

被引：14

作者：

Delval, A.

Defebvre, L.

Labyt, E.

Douay, X.

Bourriez, J. -L.

Waucquiez, N.

Derambure, P.

Destee, A.

机构：

[1] Reg Univ Hosp, Dept Clin Neurophysiol, Lille, France

[2] Reg Univ Hosp, Dept Neurol & Movement Disorders, Lille, France

[3] MENRT, Dept Neurosci, EA 2683, IFR 114, Paris, France

来源：

NEUROLOGY | 2006年 / 67卷 / 06期

关键词：

D O I：

10.1212/01.wnl.0000237528.32932.9a

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We sought to determine whether or not first-degree relatives of patients with familial Parkinson disease (FDRs) present impaired movement-related cortical activity. We studied 10 familial Parkinson disease subjects, 10 FDRs, and 10 controls and analyzed event-related mu desynchronization (ERD) and beta synchronization. Forty percent FDRs presented reduced premovement mu ERD latency, suggesting that premovement cortical activation is impaired in FDRs.

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收藏

页码：1086 / 1087

页数：2

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