Does subthalamic nucleus deep brain stimulation really improve quality of life in Parkinson's disease?

被引:28
作者
Gronchi-Perrin, Aline [1 ]
Viollier, Sarah [1 ]
Ghika, Joseph [1 ]
Combremont, Pierre [1 ]
Villemure, Jean-Guy [1 ]
Bogousslavsky, Julien [1 ]
Burkhard, Pierre R. [1 ]
Vingerhoets, Francois [1 ]
机构
[1] CHU Vaudois, Neurol Serv, Vaud Geneva Deep Brain Stimulat Program Movement, CH-1011 Lausanne, Switzerland
关键词
quality of life; Parkinson's disease; subthalamic nucleus deep brain stimulation;
D O I
10.1002/mds.20943
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We investigated the impact of subthalamic nucleus (STN) deep brain stimulation (DBS) on quality of life (QOL) in patients with advanced Parkinson's disease, as self-assessed before and after surgery by completing the Parkinson's Disease Questionnaire (PDQ39). In addition to this prospective evaluation, we asked patients postoperatively to evaluate their preoperative QOL. In the prospective assessment, results showed that patients perceived a general improvement of QOL after the STN DBS. However, when evaluated retrospectively, they tended to overestimate their preoperative functioning, therefore obscuring the improvement found prospectively. This observation highlights the impact of the method used on obtained results when assessing the effects of STN DBS. (c) 2006 Movement Disorder Society.
引用
收藏
页码:1465 / 1468
页数:4
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