How reliable is the connectivity in cortical neural networks?

被引:6
作者
Faisal, AA [1 ]
Laughlin, SB [1 ]
White, JA [1 ]
机构
[1] Univ Cambridge, Dept Zool, Cambridge CB2 3EJ, England
来源
PROCEEDING OF THE 2002 INTERNATIONAL JOINT CONFERENCE ON NEURAL NETWORKS, VOLS 1-3 | 2002年
关键词
D O I
10.1109/IJCNN.2002.1007767
中图分类号
TP18 [人工智能理论];
学科分类号
081104 [模式识别与智能系统]; 0812 [计算机科学与技术]; 0835 [软件工程]; 1405 [智能科学与技术];
摘要
Neurons use stochastic components, including ion channels, to process and transmit information. In small structures these can cause significant signal fluctuations. We developed a stochastic simulator to investigate the reliability of cortical axons. Ion channel stochasticity makes these thin axons highly susceptible to spontaneous action potentials and information rates decrease linearly with distance.
引用
收藏
页码:1661 / 1666
页数:4
相关论文
共 22 条
[1]
[Anonymous], 1992, Markov Processes: An Introduction to Physical Scientists
[2]
An energy budget for signaling in the grey matter of the brain [J].
Attwell, D ;
Laughlin, SB .
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2001, 21 (10) :1133-1145
[3]
Braitenberg V., 1998, CORTEX STAT GEOMETRY, DOI [DOI 10.1007/978-3-662-03733-1_27, 10.1007/978-3-662-03733-1]
[4]
Spontaneous action potentials due to channel fluctuations [J].
Chow, CC ;
White, JA .
BIOPHYSICAL JOURNAL, 1996, 71 (06) :3013-3021
[5]
Stochastic versions of the Hodgkin-Huxley equations [J].
Fox, RF .
BIOPHYSICAL JOURNAL, 1997, 72 (05) :2068-2074
[6]
CHANGES IN INTERSPIKE INTERVAL DURING PROPAGATION - QUANTITATIVE DESCRIPTION [J].
GEORGE, SA .
BIOLOGICAL CYBERNETICS, 1977, 26 (04) :209-213
[7]
A QUANTITATIVE DESCRIPTION OF MEMBRANE CURRENT AND ITS APPLICATION TO CONDUCTION AND EXCITATION IN NERVE [J].
HODGKIN, AL ;
HUXLEY, AF .
JOURNAL OF PHYSIOLOGY-LONDON, 1952, 117 (04) :500-544
[8]
Koch Christof, 1999, P1
[9]
The metabolic cost of neural information [J].
Laughlin, SB ;
van Steveninck, RRD ;
Anderson, JC .
NATURE NEUROSCIENCE, 1998, 1 (01) :36-41