Expedient synthesis of substituted (S)-N-(α-methylbenzyl)aziridines

被引：13

作者：

Bew, Sean P. ^{[1
]}

Hughes, David L.

Savic, Vladimir

Soapi, Katy M.

Wilson, Martin A.

机构：

[1] Univ E Anglia, Sch Chem Sci & Pharm, Norwich NR4 7TJ, Norfolk, England

[2] Fac Pharm, Dept Organ Chem, Belgrade 11000, Serbia

来源：

CHEMICAL COMMUNICATIONS | 2006年 / 33期

关键词：

D O I：

10.1039/b606033a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report for the first time that after O-acylation the conjugate addition products of (S)-N-(alpha-methylbenzyl) hydroxylamine undergo an efficient diastereoselective 3-exo-tet ring-closure reaction affording 2- and 2,3-disubstituted-N-alkylaziridines in good to excellent yields.

引用

页码：3513 / 3515

页数：3

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