N-benzylhydroxylamine addition to β-aryl enoates.: Enantioselective synthesis of β-aryl-β-amino acid precursors

被引：69

作者：

Sibi, MP ^{[1
]}

Liu, M ^{[1
]}

机构：

[1] N Dakota State Univ, Dept Chem, Fargo, ND 58105 USA

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 21期

关键词：

D O I：

10.1021/ol006500e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Chiral Lewis acid catalyzed N-benzylhydroxylamine addition to pyrrolidinone-derived enoates afforded beta-aryl-beta-amino acid derivatives in high enantiomeric purity with moderate to very good chemical efficiency.

引用

页码：3393 / 3396

页数：4

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