Growth of Chlamydia pneumoniae induces cytokine production and expression of CD14 in a human monocytic cell line

被引：120

作者：

Heinemann, M ^{[1
]}

Susa, M ^{[1
]}

Simnacher, U ^{[1
]}

Marre, R ^{[1
]}

Essig, A ^{[1
]}

机构：

[1] UNIV ULM,ABT MED MIKROBIOL & HYG,D-89081 ULM,GERMANY

来源：

INFECTION AND IMMUNITY | 1996年 / 64卷 / 11期

关键词：

D O I：

10.1128/IAI.64.11.4872-4875.1996

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Chlamydia pneumoniae was able to survive and to multiply in the human monocytic cell line Mono Mac 6, Growth of C. pneumoniae induced production of tumor necrosis factor alpha, interleukin 1 beta, and interleukin 6, as well as up-regulation of the CD14 molecule in a time-dependent manner, Infection of monocytic cells and a proinflammatory cytokine response may be important in C. pneumoniae pathogenesis.

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收藏

页码：4872 / 4875

页数：4

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共 25 条

[1] CHLAMYDIA-PNEUMONIAE - A NEW CAUSATIVE AGENT OF REACTIVE ARTHRITIS AND UNDIFFERENTIATED OLIGOARTHRITIS [J].

BRAUN, J ;

LAITKO, S ;

TREHARNE, J ;

EGGENS, U ;

WU, PH ;

DISTLER, A ;

SIEPER, J .

ANNALS OF THE RHEUMATIC DISEASES, 1994, 53 (02) :100-105

[2] DETECTION OF CHLAMYDIA-PNEUMONIAE TWAR IN HUMAN CORONARY ATHERECTOMY TISSUES [J].

CAMPBELL, LA ;

OBRIEN, ER ;

CAPPUCCIO, AL ;

KUO, CC ;

WANG, SP ;

STEWART, D ;

PATTON, DL ;

CUMMINGS, PK ;

GRAYSTON, JT .

JOURNAL OF INFECTIOUS DISEASES, 1995, 172 (02) :585-588

[3] POTENTIATION OF INTERFERON-MEDIATED INHIBITION OF CHLAMYDIA INFECTION BY INTERLEUKIN-1 IN HUMAN MACROPHAGE CULTURES [J].

CARLIN, JM ;

WELLER, JB .

INFECTION AND IMMUNITY, 1995, 63 (05) :1870-1875

[4] DETECTION OF ANTI-CHLAMYDIA PNEUMONIAE IGE IN CHILDREN WITH REACTIVE AIRWAY DISEASE [J].

EMRE, U ;

SOKOLOVSKAYA, N ;

ROBLIN, PM ;

SCHACHTER, J ;

HAMMERSCHLAG, MR .

JOURNAL OF INFECTIOUS DISEASES, 1995, 172 (01) :265-267

[5] A model of genital Chlamydia trachomatis infection using human xenografts in severe combined immunodeficiency mice [J].

Essig, A ;

Rudolphi, A ;

Heinemann, M ;

Rosenthal, H ;

Kaufmann, R ;

Reimann, J ;

Marre, R .

INFECTION AND IMMUNITY, 1996, 64 (06) :2300-2307

[6] SECRETION OF INTERLEUKIN-8 FOLLOWING PHAGOCYTOSIS OF MYCOBACTERIUM-TUBERCULOSIS BY HUMAN MONOCYTE CELL-LINES [J].

FRIEDLAND, JS ;

REMICK, DG ;

SHATTOCK, R ;

GRIFFIN, GE .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1992, 22 (06) :1373-1378

[7] INFECTIONS CAUSED BY CHLAMYDIA-PNEUMONIAE STRAIN TWAR [J].

GRAYSTON, JT .

CLINICAL INFECTIOUS DISEASES, 1992, 15 (05) :757-763

[8] ASSOCIATION OF CHLAMYDIA-PNEUMONIAE (STRAIN TWAR) INFECTION WITH WHEEZING, ASTHMATIC BRONCHITIS, AND ADULT-ONSET ASTHMA [J].

HAHN, DL ;

DODGE, RW ;

GOLUBJATNIKOV, R .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1991, 266 (02) :225-230

[9] THE INFLAMMATORY CYTOKINE RESPONSE TO CHLAMYDIA-TRACHOMATIS INFECTION IS ENDOTOXIN MEDIATED [J].

INGALLS, RR ;

RICE, PA ;

QURESHI, N ;

TAKAYAMA, K ;

LIN, JS ;

GOLENBOCK, DT .

INFECTION AND IMMUNITY, 1995, 63 (08) :3125-3130

[10] CHLAMYDIA-TRACHOMATIS PNEUMONIA INDUCES INVIVO PRODUCTION OF INTERLEUKIN-1 AND INTERLEUKIN-6 [J].

MAGEE, DM ;

SMITH, JG ;

BLEICKER, CA ;

CARTER, CJ ;

BONEWALD, LF ;

SCHACHTER, J ;

WILLIAMS, DM .

INFECTION AND IMMUNITY, 1992, 60 (03) :1217-1220