The biological relevance of polykaryons in the immune response

被引：30

作者：

Fais, S

Burgio, VL

Capobianchi, MR

Gessani, S

Pallone, F

Belardelli, F

机构：

[1] UNIV ROMA LA SAPIENZA,INST INTERNAL MED,I-00161 ROME,ITALY

[2] UNIV ROMA LA SAPIENZA,INST VIROL,I-00185 ROME,ITALY

[3] UNIV REGGIO CALABRIA,DEPT EXPT MED,CATANZARO,ITALY

来源：

IMMUNOLOGY TODAY | 1997年 / 18卷 / 11期

关键词：

D O I：

10.1016/S0167-5699(97)01148-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Peripheral blood monocyte-derived multinucleated giant cells are a well-known feature of chronic inflammatory conditions. Similarly, virus-induced syncytin derived from CD4(+) cells are considered to be typical of human immunodeficiency virus infection under culture conditions. Here, Stefano Fais and colleagues summarize recent experimental results comparing the mechanisms underlying the formation and fate of these two different polykaryons, discussing their putative role in the immune response.

引用

页码：522 / 527

页数：6

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