PheP, a putative amino acid permease of Staphylococcus aureus, contributes to survival in vivo and during starvation

被引：15

作者：

Horsburgh, MJ

Wiltshire, MD

Crossley, H

Ingham, E

Foster, SJ

机构：

[1] Univ Sheffield, Dept Mol Biol & Biotechnol, Sheffield S10 2TH, S Yorkshire, England

[2] Univ Leeds, Div Microbiol, Leeds LS2 9JT, W Yorkshire, England

来源：

INFECTION AND IMMUNITY | 2004年 / 72卷 / 05期

关键词：

D O I：

10.1128/IAI.72.5.3073-3076.2004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

PheP, a putative amino acid permease in Staphylococcus aureus, contributes to starvation survival under glucose-limiting conditions and virulence. A pheP mutation led to poor growth after microaerobic or anaerobic incubation on pig serum agar, which was recovered by phenylalanine addition. Genetic complementation of pheP restored growth and starvation survival.

引用

页码：3073 / 3076

页数：4

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