Reinventing phage therapy: are the parts greater than the sum?

被引:113
作者
Fischetti, Vincent A. [1 ]
Nelson, Daniel [1 ]
Schuch, Raymond [1 ]
机构
[1] Rockefeller Univ, Lab Bacterial Pathogenesis & Immunol, New York, NY 10021 USA
关键词
D O I
10.1038/nbt1206-1508
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Although whole phage continue to generate interest as an alternative to antibiotics, focus is shifting to the use of purified phage components as antibacterial agents. © 2006 Nature Publishing Group.
引用
收藏
页码:1508 / 1511
页数:4
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共 43 条
[31]  
Pennazio S, 2006, RIV BIOL-BIOL FORUM, V99, P103
[32]   Phage-inspired antibiotics? [J].
Projan, S .
NATURE BIOTECHNOLOGY, 2004, 22 (02) :167-168
[33]   A bacteriolytic agent that detects and kills Bacillus anthracis [J].
Schuch, R ;
Nelson, D ;
Fischetti, VA .
NATURE, 2002, 418 (6900) :884-889
[34]   Application of bacteriophages to control intestinal Escherichia coli O157:H7 levels in ruminants [J].
Sheng, Haiqing ;
Knecht, Hannah J. ;
Kudva, Indira T. ;
Hovde, Carolyn J. .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2006, 72 (08) :5359-5366
[35]   Bacteriophage therapy [J].
Sulakvelidze, A ;
Alavidze, Z ;
Morris, JG .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (03) :649-659
[36]   Viruses in the sea [J].
Suttle, CA .
NATURE, 2005, 437 (7057) :356-361
[37]   Old dogma, new tricks - 21st century phage therapy [J].
Thiel, K .
NATURE BIOTECHNOLOGY, 2004, 22 (01) :31-36
[38]   Are viruses driving microbial diversification and diversity? [J].
Weinbauer, MG ;
Rassoulzadegan, F .
ENVIRONMENTAL MICROBIOLOGY, 2004, 6 (01) :1-11
[39]   Use of genetically engineered phage to deliver antimicrobial agents to bacteria: an alternative therapy for treatment of bacterial infections [J].
Westwater, C ;
Kasman, LM ;
Schofield, DA ;
Werner, PA ;
Dolan, JW ;
Schmidt, MG ;
Norris, JS .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (04) :1301-1307
[40]   Bacteriophages - potential for application in wastewater treatment processes [J].
Withey, S ;
Cartmell, E ;
Avery, LM ;
Stephenson, T .
SCIENCE OF THE TOTAL ENVIRONMENT, 2005, 339 (1-3) :1-18