Homeostasis in Infected Epithelia: Stem Cells Take the Lead

被引：38

作者：

Pitsouli, Chrysoula ^{[1
]}

Apidianakis, Yiorgos ^{[3
,4
]}

Perrimon, Norbert ^{[1
,2
]}

机构：

[1] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Howard Hughes Med Inst, Boston, MA 02115 USA

[3] Massachusetts Gen Hosp, Dept Surg, Boston, MA 02114 USA

[4] Massachusetts Gen Hosp, Shriners Burns Inst, Boston, MA 02114 USA

来源：

CELL HOST & MICROBE | 2009年 / 6卷 / 04期

关键词：

UROPATHOGENIC ESCHERICHIA-COLI; DROSOPHILA MIDGUT; BACTERIAL-INFECTION; URINARY-TRACT; HOST DEFENSES; SELF-RENEWAL; PROLIFERATION; REGENERATION; ACTIVATION; INTESTINE;

D O I：

10.1016/j.chom.2009.10.001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

To maintain tissue homeostasis and avoid disease, epithelial cells damaged by pathogens need to be readily replenished, and this is mainly achieved by the activation of stem cells. In this Short Review, we discuss recent developments in the exciting field of host epithelia-pathogen interaction in Drosophila as well as in mammals.

引用

页码：301 / 307

页数：7

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