Circulating and Disseminated Tumor Cells in the Clinical Management of Breast Cancer Patients: Unanswered Questions

被引：22

作者：

Amadori, A. ^{[1
]}

Rossi, E. ^{[1
]}

Zamarchi, R. ^{[1
]}

Carli, P. ^{[1
]}

Pastorelli, D. ^{[1
]}

Jirillo, A. ^{[1
]}

机构：

[1] Ist Oncol Veneto IRCCS, IT-35128 Padua, Italy

来源：

ONCOLOGY | 2009年 / 76卷 / 06期

关键词：

Breast cancer; Cell growth; Circulating tumor cells; Disseminated tumor cells; Prognostic factor; BONE-MARROW MICROMETASTASES; POLYMERASE-CHAIN-REACTION; MINIMAL RESIDUAL DISEASE; RNA-POSITIVE CELLS; PERIPHERAL-BLOOD; ADJUVANT CHEMOTHERAPY; EPITHELIAL-CELLS; CARCINOMA-CELLS; EARLY RELAPSE; STEM-CELL;

D O I：

10.1159/000215581

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Breast cancer is the most common cancer in women. Although survival rates have improved with the use of new therapeutic agents, many issues remain unresolved and new predictive and prognostic factors are needed in clinical practice. Several studies have suggested a prognostic and predictive role for circulating and disseminated tumor cells in metastatic disease and adjuvant treatment. Because of recent technological advances, oncologists have gained a new perspective on this disease. Circulating tumor cells could be both a new tumor marker as well as a tool to gain novel insight into the natural history of this neoplastic disease. Copyright (C) 2009 S. Karger AG, Basel

引用

页码：375 / 386

页数：12

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