Synthesis of trisubstituted alkenes via olefin cross-metathesis

被引：312

作者：

Chatterjee, AK ^{[1
]}

Grubbs, RH ^{[1
]}

机构：

[1] CALTECH, Arnold & Mabel Beckman Labs Chem Synthesis, Div Chem & Chem Engn, Pasadena, CA 91125 USA

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 11期

关键词：

D O I：

10.1021/ol991023p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Trisubstituted alkenes have been prepared for the first time via intermolecular olefin cross metathesis, using 1,3-dimesityl -4,5-dihydroimidazol- 5-ylidene ruthenium alkylidene complexes 3a,b in good yields with moderate E selectivity. In addition, protected alcohols near the geminal disubstituted olefin improve reactivity for cross-metathesis.

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收藏

页码：1751 / 1753

页数：3

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