Usefulness of the response of flow velocity in the left anterior descending coronary artery to the cold pressor test for evaluating endothelium-dependent vascular relaxation in the coronary microvasculature by transesophageal echocardiography in subjects with angiographically normal coronary arteries

被引:20
作者
Chandraratna, PAN [1 ]
Nimalasuriya, AR [1 ]
Vlachonassios, KD [1 ]
Mathews, SJ [1 ]
Kedes, W [1 ]
Marwah, OS [1 ]
Saad, M [1 ]
机构
[1] Univ So Calif, Sch Med, Div Cardiol, Med Ctr, Los Angeles, CA 90033 USA
关键词
D O I
10.1016/S0002-9149(99)00576-7
中图分类号
R5 [内科学];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
Measurement of flow velocity in the left anterior descending coronary artery by transesophageal echocardiography in subjects without risk factors for coronary artery disease (group 1) and in subjects with normal coronary arteries but conditions associated with endothelial dysfunction (group 2) revealed that there was a significantly impaired coronary flow velocity response to the cold presser test in group 2 subjects. Thus, transesophageal echocardiography provides a minimally invasive tool for the functional assessment of endothelium and can be valuable in evaluating endothelial dysfunction and recovery in a variety of disease states.
引用
收藏
页码:1362 / +
页数:5
相关论文
共 16 条
[1]
CIGARETTE-SMOKING IS ASSOCIATED WITH DOSE-RELATED AND POTENTIALLY REVERSIBLE IMPAIRMENT OF ENDOTHELIUM-DEPENDENT DILATION IN HEALTHY-YOUNG ADULTS [J].
CELERMAJER, DS ;
SORENSEN, KE ;
GEORGAKOPOULOS, D ;
BULL, C ;
THOMAS, O ;
ROBINSON, J ;
DEANFIELD, JE .
CIRCULATION, 1993, 88 (05) :2149-2155
[2]
Comparison of intracoronary Doppler guide wire and transesophageal echocardiography in measurement of flow velocity and coronary flow reserve in the left anterior descending coronary artery [J].
Gadallah, S ;
Thaker, KB ;
Kawanishi, D ;
Mehra, A ;
Lau, S ;
Rashtian, M ;
Chandraratna, PAN .
AMERICAN HEART JOURNAL, 1998, 135 (01) :38-42
[3]
EFFECTS OF INTRAAORTIC BALLOON COUNTERPULSATION ON BOW VELOCITY IN STENOTIC LEFT MAIN CORONARY-ARTERIES FROM TRANSESOPHAGEAL ECHOCARDIOGRAPHY [J].
HUTCHISON, SJ ;
THAKER, KB ;
CHANDRARATNA, PAN .
AMERICAN JOURNAL OF CARDIOLOGY, 1994, 74 (10) :1063-1065
[4]
Determination of coronary flow measurements by transesophageal echocardiography: Dependence of flow velocity reserve on the location of stenosis [J].
Hutchison, SJ ;
Soldo, SJ ;
Gadallah, S ;
Kawanishi, DT ;
Chandraratna, PAN .
AMERICAN HEART JOURNAL, 1997, 133 (01) :44-52
[5]
IMPAIRED ENDOTHELIUM-DEPENDENT VASODILATION IN PATIENTS WITH INSULIN-DEPENDENT DIABETES-MELLITUS [J].
JOHNSTONE, MT ;
CREAGER, SJ ;
SCALES, KM ;
CUSCO, JA ;
LEE, BK ;
CREAGER, MA .
CIRCULATION, 1993, 88 (06) :2510-2516
[6]
Mechanisms of coronary flow reserve impairment in human hypertension - An integrated approach by transthoracic and transesophageal echocardiography [J].
Kozakova, M ;
Palombo, C ;
Pratali, L ;
Pittella, G ;
Galetta, F ;
LAbbate, A .
HYPERTENSION, 1997, 29 (02) :551-559
[7]
Comparison between positron emission tomography myocardial perfusion imaging and intracoronary Doppler flow velocity measurements at rest and during cold pressor testing in angiographically normal coronary arteries in patients with one-vessel coronary artery disease [J].
Meeder, JG ;
Peels, HO ;
Blanksma, PK ;
Tan, ES ;
Pruim, J ;
vanderWall, EE ;
Vaalburg, W ;
Lie, KI .
AMERICAN JOURNAL OF CARDIOLOGY, 1996, 78 (05) :526-531
[8]
DILATION OF NORMAL AND CONSTRICTION OF ATHEROSCLEROTIC CORONARY-ARTERIES CAUSED BY THE COLD PRESSOR TEST [J].
NABEL, EG ;
GANZ, P ;
GORDON, JB ;
ALEXANDER, RW ;
SELWYN, AP .
CIRCULATION, 1988, 77 (01) :43-52
[9]
CORONARY VASCULAR RESERVE IN HUMANS - A CRITICAL-REVIEW OF METHODS OF EVALUATION AND OF INTERPRETATION OF THE RESULTS [J].
NITENBERG, A ;
ANTONY, I .
EUROPEAN HEART JOURNAL, 1995, 16 :7-21
[10]
IMPAIRMENT OF FLOW-DEPENDENT CORONARY DILATION IN HYPERTENSIVE PATIENTS - DEMONSTRATION BY COLD PRESSOR TEST INDUCED FLOW VELOCITY INCREASE [J].
NITENBERG, A ;
ANTONY, I ;
APTECAR, E ;
ARNOULT, F ;
LEREBOURS, G .
AMERICAN JOURNAL OF HYPERTENSION, 1995, 8 (05) :S13-S18