Bis(phenanthroline)-ethylenediamine conjugate displays excimer fluorescence upon binding with DNA

被引:27
作者
Hayashi, K [1 ]
Akutsu, H [1 ]
Ozaki, H [1 ]
Sawai, H [1 ]
机构
[1] Gunma Univ, Fac Engn, Dept Appl Chem, Kiryu, Gumma 3768515, Japan
关键词
D O I
10.1039/b316126a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
1,2-Bis(1,10-phenanthrolin-2-yl)ethylenediamine (1) displays a unique long-life time excimer fluorescence at 528 nm by binding with calf thymus DNA, while its monomer fluorescence at 400 nm shows a decrease upon binding with DNA.
引用
收藏
页码:1386 / 1387
页数:2
相关论文
共 26 条
[1]   Practical synthesis of unsymmetrical polyamine amides [J].
Blagbrough, IS ;
Geall, AJ .
TETRAHEDRON LETTERS, 1998, 39 (5-6) :439-442
[2]   Model studies indicate that copper phenanthroline induces direct strand breaks via β-elimination of the 2′-deoxyribonolactone intermediate observed in enediyne mediated DNA damage [J].
Chen, TQ ;
Greenberg, MM .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (15) :3815-3816
[3]   Photophysics of cationic 5,10,15,20-tetrakis-(4-N-methylpyridyl)porphyrin bound to DNA, [poly(dA-dT)](2) and [poly(dG-dC)](2): on a possible charge transfer process between guanine and porphyrin in its excited singlet state [J].
Chirvony, VS ;
Galievsky, VA ;
Kruk, NN ;
Dzhagarov, BM ;
Turpin, PY .
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 1997, 40 (02) :154-162
[4]   VISCOSITY AND SEDIMENTATION STUDY OF SONICATED DNA-PROFLAVINE COMPLEXES [J].
COHEN, G ;
EISENBERG, H .
BIOPOLYMERS, 1969, 8 (01) :45-+
[5]   Recognition and reaction of metallointercalators with DNA [J].
Erkkila, KE ;
Odom, DT ;
Barton, JK .
CHEMICAL REVIEWS, 1999, 99 (09) :2777-2795
[6]  
GUERZO D, 2002, INORG CHEM, V41, P938
[7]   CHARGE-TRANSFER ABSORPTION AND EMISSION OF CU(NN)2+ SYSTEMS [J].
ICHINAGA, AK ;
KIRCHHOFF, JR ;
MCMILLIN, DR ;
DIETRICHBUCHECKER, CO ;
MARNOT, PA ;
SAUVAGE, JP .
INORGANIC CHEMISTRY, 1987, 26 (25) :4290-4292
[8]  
KELLEY L, 1993, J AM CHEM SOC, V115, P6699
[9]  
Klessinger M., 1995, EXCITED STATES PHOTO, P278
[10]   Ruthenium(II) complexes with 1,4,5,8,9,12-hexaazatriphenylene and 1,4,5,8-tetraazaphenanthrene ligands: Key role played by the photoelectron transfer in DNA cleavage and adduct formation [J].
Lecomte, JP ;
KirschDeMesmaeker, A ;
Feeney, MM ;
Kelly, JM .
INORGANIC CHEMISTRY, 1995, 34 (26) :6481-6491