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Structure and electron transfer mechanism of pyruvate:ferredoxin oxidoreductase

被引：61
作者：
Charon, MH
Volbeda, A
Chabriere, E
Pieulle, L
Fontecilla-Camps, JC
机构：
[1] Inst Biol Struct JP Ebel, Cristallog & Cristallogenese Prot Lab, CNRS, CEA, F-38027 Grenoble 1, France
[2] CNRS, Unite Bioenerget & Ingn Prot, F-13402 Marseille, France
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 1999年 / 9卷 / 06期
关键词：
D O I：
10.1016/S0959-440X(99)00027-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The first crystal structure of pyruvate:ferredoxin oxidoreductase to be determined has provided significant new information on its structural organization and redox chemistry. Spectroscopic analyses of a: radical reaction intermediate have shed more light on its thiamin-based mechanism of catalysis. Different approaches have been used to study the interaction between the enzyme and ferredoxin, its redox partner.
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收藏
页码：663 / 669
页数：7
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