Structure and electron transfer mechanism of pyruvate:ferredoxin oxidoreductase

被引：61

作者：

Charon, MH

Volbeda, A

Chabriere, E

Pieulle, L

Fontecilla-Camps, JC

机构：

[1] Inst Biol Struct JP Ebel, Cristallog & Cristallogenese Prot Lab, CNRS, CEA, F-38027 Grenoble 1, France

[2] CNRS, Unite Bioenerget & Ingn Prot, F-13402 Marseille, France

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1999年 / 9卷 / 06期

关键词：

D O I：

10.1016/S0959-440X(99)00027-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The first crystal structure of pyruvate:ferredoxin oxidoreductase to be determined has provided significant new information on its structural organization and redox chemistry. Spectroscopic analyses of a: radical reaction intermediate have shed more light on its thiamin-based mechanism of catalysis. Different approaches have been used to study the interaction between the enzyme and ferredoxin, its redox partner.

引用

页码：663 / 669

页数：7

共 62 条

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