Modified polyelectrolyte microcapsules as smart defense systems

被引：84

作者：

Shchukin, DG ^{[1
]}

Shutava, T

Shchukina, E

Sukhorukov, GB

Lvov, YM

机构：

[1] Louisiana Tech Univ, Inst Micromfg, Ruston, LA 71272 USA

[2] Byelarussian Acad Sci, Inst Bioorgan Chem, Minsk 220141, BELARUS

[3] Max Planck Inst Colloids & Interfaces, D-14424 Potsdam, Germany

来源：

CHEMISTRY OF MATERIALS | 2004年 / 16卷 / 18期

关键词：

D O I：

10.1021/cm049506x

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A new type of protective microcontainer, capable of preventing oxidation of encapsulated compounds by low molecular weight oxidizing agents, was demonstrated. These microcontainers (microcapsules) are hollow spheres with the shell made of layer-by-layer assembled polyelectrolytes with an engineered outermost layer. The protecting ability of the developed polyelectrolyte capsules was monitored by oxidation of encapsulated bovine serum albumin by H2O2 dissolved in aqueous solution. Different catalysts for H2O2 decomposition (catalase, Fe3O4 nanoparticles) were deposited onto the polyelectrolyte shell to increase the protection efficiency. The highest protection activity was observed for poly(allylamine)/poly(styrene sulfonate) capsules containing nano-Fe3O4 in the polyelectrolyte shell.

引用

页码：3446 / 3451

页数：6

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