Epomusenins A and B, two acetogenins from fruits of Rollinia mucosa

被引:31
作者
Chen, YY
Chang, FR
Yen, HF
Wu, YC
机构
[1] KAOHSIUNG MED COLL,GRAD INST NAT PROD,KAOHSIUNG 807,TAIWAN
[2] TAIWAN AGR RES INST,CHIA YI AGR EXPT STN,CHIAYI 600,TAIWAN
关键词
Rollinia mucosa; annonaceae; fruits; olefinic; epoxy-acetogenins; epomusenins; rolliniastatin-1; rolliniastatin-2; squamocin;
D O I
10.1016/0031-9422(96)00050-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Chromatography of an ethyl acetate extract of the fruits of Rollinia mucosa led to the isolation of two new gamma-lactone acetogenins, epomusenins A and B, which are the first examples of the rare C-37-type annonaceous acetogenins having an epoxide and a double bond along the aliphatic chain in place of the usual tetrahydrofuran moeity. The three known acetogenins, rolliniastatin-1, rolliniastatin-2 and squamocin were also isolated. The structures were established by means of one and two dimensional NMR experiments.
引用
收藏
页码:1081 / 1083
页数:3
相关论文
共 14 条
[11]  
SHI GE, 1995, HETEROCYCLES, V41, P1785
[12]   ANNORETICUIN AND ISOANNORETICUIN - 2 NEW CYTOTOXIC ACETOGENINS FROM ANNONA-RETICULATA [J].
WU, YC ;
CHANG, FR ;
DUH, CY ;
WANG, SK .
HETEROCYCLES, 1992, 34 (04) :667-674
[13]   DIEPOXYMONTIN, A NOVEL ACETOGENIN FROM ANNONA-MONTANA [J].
WU, YC ;
CHANG, FR ;
CHEN, KS ;
LIANG, SC ;
LEE, MR .
HETEROCYCLES, 1994, 38 (07) :1475-1478
[14]  
WU YC, 1995, CHEMISTRY, V53, P76