Supported ionic liquid asymmetric catalysis. A new method for chiral catalysts recycling. The case of proline-catalyzed aldol reaction

被引：120

作者：

Gruttadauria, M ^{[1
]}

Riela, S ^{[1
]}

Lo Meo, P ^{[1
]}

D'Anna, F ^{[1
]}

Noto, R ^{[1
]}

机构：

[1] Univ Palermo, Dipartimento Chim Organ E Paterno, I-90128 Palermo, Italy

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 32期

关键词：

Aldols; silica gel; supported reagents;

D O I：

10.1016/j.tetlet.2004.06.066

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new method for chiral catalysts recycling, based on the supported ionic liquid asymmetric catalysis concept, has been developed. This concept involves the treatment of a monolayer of covalently attached ionic liquid on the surface of silica gel with additional ionic liquid. These layers serve as the reaction phase in which the homogeneous chiral catalyst is dissolved. As first application of this concept the L-proline-catalyzed aldol reaction has been carried out. Good yields and ee values, comparable with those obtained under homogeneous conditions have been obtained. Moreover, this material shows high regenerability. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：6113 / 6116

页数：4

共 31 条

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