The relationship between structure and function for the sulfite reductases

被引：130

作者：

Crane, BR

Getzoff, ED

机构：

[1] Department of Molecular Biology, Scripps Research Institute, San Diego, CA 92037

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1996年 / 6卷 / 06期

关键词：

D O I：

10.1016/S0959-440X(96)80003-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The six-electron reductions of sulfite to sulfide and nitrite to ammonia, fundamental to early and contemporary life, are catalyzed by diverse sulfite and nitrite reductases that share an unusual prosthetic assembly in their active centers, namely siroheme covalently linked to an Fe4S4 cluster. The recently determined crystallographic structure of the sulfite reductase hemoprotein from Escherichia coli complements extensive biochemical and spectroscopic studies in revealing structural features that are key for the catalytic mechanism and in suggesting a common symmetric structural unit for this diverse family of enzymes.

引用

收藏

页码：744 / 756

页数：13

相关论文

共 93 条

[51] ELECTRONIC-PROPERTIES OF THE DISSIMILATORY SULFITE REDUCTASE FROM DESULFOVIBRIO-VULGARIS (HILDENBOROUGH) - COMPARATIVE-STUDIES OF OPTICAL-SPECTRA AND RELATIVE REDUCTION POTENTIALS FOR THE [FE4S4]-SIROHAEM PROSTHETIC CENTERS [J].

LUI, SM ;

SORIANO, A ;

COWAN, JA .

BIOCHEMICAL JOURNAL, 1994, 304 :441-447

[52]

Lui SM, 1996, INORG CHIM ACTA, V242, P25

[53] ENZYMATIC REDUCTION OF INORGANIC ANIONS - PRE-STEADY-STATE KINETIC-ANALYSIS OF THE DISSIMILATORY SULFITE REDUCTASE (DESULFOVIRIDIN) FROM DESULFOVIBRIO-VULGARIS (HILDENBOROUGH) - MECHANISTIC IMPLICATIONS [J].

LUI, SM ;

SORIANO, A ;

COWAN, JA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (23) :10483-10486

[54] CONFORMATIONAL GATING OF THE DISSIMILATORY SULFITE REDUCTASE FROM DESULFOVIBRIO-VULGARIS (HILDENBOROUGH) - SYNTHESIS, CHARACTERIZATION, AND STOPPED-FLOW KINETICS STUDIES OF 1,5-IAEDANS-LABELED DESULFOVIRIDIN [J].

LUI, SM ;

COWAN, JA .

BIOCHEMISTRY, 1994, 33 (37) :11209-11216

[55] DIRECT REVERSIBLE PROTEIN ELECTROCHEMISTRY AT A PYROLYTIC-GRAPHITE ELECTRODE - CHARACTERIZATION OF THE REDOX THERMODYNAMICS OF THE FE4S4 SIROHEME PROSTHETIC CENTER IN THE HEXAMERIC DISSIMILATORY SULFITE REDUCTASE AND THE MONOMERIC ASSIMILATORY SULFITE REDUCTASE FROM DESULFOVIBRIO-VULGARIS (HILDENBOROUGH) - SYSTEMATIC PH TITRATION EXPERIMENTS AND IMPLICATIONS FOR ACTIVE-SITE CHEMISTRY [J].

LUI, SM ;

COWAN, JA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (25) :11538-11549

[56] NITRITE REDUCTASE GENE FROM SYNECHOCOCCUS SP PCC-7942 - HOMOLOGY BETWEEN CYANOBACTERIAL AND HIGHER-PLANT NITRITE REDUCTASES [J].

LUQUE, I ;

FLORES, E ;

HERRERO, A .

PLANT MOLECULAR BIOLOGY, 1993, 21 (06) :1201-1205

[57]

MCREE DE, 1986, J BIOL CHEM, V261, P277

[58] ANALYSIS OF A SIROHEME MODEL-COMPOUND - CORE-SIZE DEPENDENCE OF RESONANCE RAMAN BANDS AND THE SIROHEME SPIN STATE IN SULFITE REDUCTASE [J].

MELAMED, D ;

SULLIVAN, EP ;

PRENDERGAST, K ;

STRAUSS, SH ;

SPIRO, TG .

INORGANIC CHEMISTRY, 1991, 30 (06) :1308-1319

[59] CHARACTERIZATION OF 2 DISSIMILATORY SULFITE REDUCTASES (DESULFORUBIDIN AND DESULFOVIRIDIN) FROM THE SULFATE-REDUCING BACTERIA - MOSSBAUER AND ELECTRON-PARAMAGNETIC-RES STUDIES [J].

MOURA, I ;

LEGALL, J ;

LINO, AR ;

PECK, HD ;

FAUQUE, G ;

XAVIER, AV ;

DERVARTANIAN, DV ;

MOURA, JJG ;

HUYNH, BH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (04) :1075-1082

[60]

MOURA I, 1994, METHOD ENZYMOL, V243, P296

← 1 2 3 4 5 6 7 8 9 10 →