Transient tinnitus suppression induced by repetitive transcranial magnetic stimulation and transcranial direct current stimulation

被引：157

作者：

Fregni, F.

Marcondes, R.

Boggio, P. S.

Marcolin, M. A.

Rigonatti, S. P.

Sanchez, T. G.

Nitsche, M. A.

Pascual-Leone, A.

机构：

[1] Harvard Univ, Sch Med, Harvard Ctr Noninvas Brain Stimulat, Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA

[2] Univ Sao Paulo, Otolaryngol & Psychiat Dept, Hosp & Clin, Sao Paulo, Brazil

[3] Univ Gottingen, Dept Clin Neurophysiol, D-3400 Gottingen, Germany

来源：

EUROPEAN JOURNAL OF NEUROLOGY | 2006年 / 13卷 / 09期

关键词：

tinnitus; transcranial direct current stimulation; transcranial magnetic stimulation; AUDITORY-CORTEX; MOTOR CORTEX; EXCITABILITY; POLARIZATION; PERCEPTION; RTMS;

D O I：

10.1111/j.1468-1331.2006.01414.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Modulation of activity in the left temporoparietal area (LTA) by 10 Hz repetitive transcranial magnetic stimulation (rTMS) results in a transient reduction of tinnitus. We aimed to replicate these results and test whether transcranial direct current stimulation (tDCS) of LTA could yield similar effect. Patients with tinnitus underwent six different types of stimulation in a random order: 10-Hz rTMS of LTA, 10-Hz rTMS of mesial parietal cortex, sham rTMS, anodal tDCS of LTA, cathodal tDCS of LTA and sham tDCS. A non-parametric analysis of variance showed a significant main effect of type of stimulation (P = 0.002) and post hoc tests showed that 10-Hz rTMS and anodal tDCS of LTA resulted in a significant reduction of tinnitus. These effects were short lasting. These results replicate the findings of the previous study and, in addition, show preliminary evidence that anodal tDCS of LTA induces a similar transient tinnitus reduction as high-frequency rTMS.

引用

页码：996 / 1001

页数：6

共 25 条

[1] Direct current stimulation over MT+/V5 modulates motion aftereffect in humans [J].