Systems biology and new technologies enable predictive and preventative medicine

被引：743

作者：

Hood, L ^{[1
]}

Heath, JR

Phelps, ME

Lin, BY

机构：

[1] Inst Syst Biol, Seattle, WA USA

[2] CALTECH, Dept Chem, Pasadena, CA 91125 USA

[3] Univ Calif Los Angeles, David Geffen Sch Med, Dept Mol & Med Pharmacol, Los Angeles, CA USA

来源：

SCIENCE | 2004年 / 306卷 / 5696期

关键词：

D O I：

10.1126/science.1104635

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Systems approaches to disease are grounded in the idea that disease-perturbed protein and gene regulatory networks differ from their normal counterparts; we have been pursuing the possibility that these differences may be reflected by multiparameter measurements of the blood. Such concepts are transforming current diagnostic and therapeutic approaches to medicine and, together with new technologies, wilt enable a predictive and preventive medicine that will lead to personalized medicine.

引用

页码：640 / 643

页数：4

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