Synthesis of oxacalixarenes incorporating nitrogen heterocycles: Evidence for thermodynamic control

被引：83

作者：

Katz, Jeffrey L. ^{[1
]}

Geller, Bram J. ^{[1
]}

Conry, Rebecca R. ^{[1
]}

机构：

[1] Colby Coll, Dept Chem, Waterville, ME 04901 USA

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 13期

关键词：

D O I：

10.1021/ol060823e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Oxacalix[2]arene[2] hetarenes are formed in a single step by cyclooligomerization of meta-diphenols with meta-dichlorinated azaheterocycles. The high selectivity for cyclic tetramer formation results from thermodynamic product control. Macrocycles as large as oxacalix[5] arene[5]hetarenes have been isolated under nonequilibrating conditions.

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页码：2755 / 2758

页数：4

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