An inexpensive and efficient copper catalyst for N-arylation of amines, Amides and nitrogen-containing heterocycles

被引：165

作者：

Guo, Xun

Rao, Honghua

Fu, Hua ^{[1
]}

Jiang, Yuyang

Zhao, Yufen

机构：

[1] Tsing Hua Univ, Dept Chem, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Minist Educ, Beijing 100084, Peoples R China

[2] Tsing Hua Univ, Key Lab Chem Biol, Grad Sch Shenzhen, Shenzhen 518057, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2006年 / 348卷 / 15期

关键词：

arylation; copper; cross-coupling; homogeneous catalysis; N; O ligands;

D O I：

10.1002/adsc.200606198

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An inexpensive and efficient catalyst system has been developed for the N-arylation of nitrogen-containing compounds including a variety of amines, amides, indole and imidazole. This simple protocol uses CuI as the catalyst, commercial available pipecolinic acid as the new ligand, K2CO3 as the base and DMF as the solvent.

引用

页码：2197 / 2202

页数：6

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