Theoretical assessment of FePt nanoparticles as heating elements for magnetic hyperthermia

被引:172
作者
Maenosono, Shinya [1 ]
Saita, Soichiro
机构
[1] Univ Tokyo, Dept Chem Syst Engn, Tokyo 1138656, Japan
[2] Mitsubishi Chem Grp Sci & Technol Res Ctr Inc, Kanagawa 2278502, Japan
关键词
bioheat transfer equation; cancer treatment; hyperthermia; iron-platinum nanoparticle;
D O I
10.1109/TMAG.2006.872198
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
FePt magnetic nanoparticles (MNPs) are expected to be a high-performance nanoheater for magnetic hyperthermia because of their high Curie temperature, high saturation magnetization, and high chemical stability. Here, we present a theoretical performance assessment of chemically disordered fcc-phase FePt MNPs. We calculate heat generation and heat transfer in the tissue when an MNP-loaded tumor is placed on an external alternating magnetic field. For comparison, We estimate the performances of magnetite, maghemite, FeCo, and L(1)0-phase FePt MNPs. We find that an fcc FePt MNP has a. superior ability in magnetic hyperthermia.
引用
收藏
页码:1638 / 1642
页数:5
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