A comparison of regional and general anaesthesia for total replacement of the hip or knee A META-ANALYSIS

被引：160

作者：

Hu, S. ^{[1
]}

Zhang, Z. -Y. ^{[1
]}

Hua, Y. -Q. ^{[1
]}

Li, J. ^{[1
]}

Cai, Z. -D. ^{[1
]}

机构：

[1] Second Mil Med Univ, Shanghai 200433, Peoples R China

来源：

JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME | 2009年 / 91B卷 / 07期

关键词：

DEEP-VEIN THROMBOSIS; PATIENT-CONTROLLED ANALGESIA; EPIDURAL-ANESTHESIA; SPINAL-ANESTHESIA; ORTHOPEDIC-SURGERY; VENOUS THROMBOSIS; CONTROLLED-TRIALS; ELDERLY-PATIENTS; BLOOD-LOSS; ARTHROPLASTY;

D O I：

10.1302/0301-620X.91B7.21538

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

We performed a meta-analysis to evaluate the relative efficacy of regional and general anaesthesia in patients undergoing total hip or knee replacement. A comprehensive search for relevant studies was performed in PubMed (1966 to April 2008), EMBASE (1969 to April 2008) and the Cochrane Library. Only randomised studies comparing regional and general anaesthesia for total hip or knee replacement were included. We identified 21 independent, randomised clinical trials. A random-effects model was used to calculate all effect sizes. Pooled results from these trials showed that regional anaesthesia reduces the operating time (odds ratio (OR) -0.19; 95% confidence interval (CI) -0.33 to -0.05), the need for transfusion (OR 0.45; 95% CI 0.22 to 0.94) and the incidence of thromboembolic disease (deep-vein thrombosis OR 0.45, 95% CI 0.24 to 0.84; pulmonary embolism OR 0.46, 95% CI 0.29 to 0.80). Regional anaesthesia therefore seems to improve the outcome of patients undergoing total hip or knee replacement.

引用

页码：935 / 942

页数：8

共 43 条

[41] Randomized trial of epidural versus general anesthesia - Outcomes after primary total replacement [J].