Catechol pendant polystyrene for solid-phase synthesis

被引：33

作者：

Yang, WQ ^{[1
]}

Gao, XM ^{[1
]}

Springsteen, G ^{[1
]}

Wang, BH ^{[1
]}

机构：

[1] N Carolina State Univ, Dept Chem, Raleigh, NC 27695 USA

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 36期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(02)01370-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A catechol pendant polystyrene polymer was prepared from the Merrifield resin via a convenient procedure with high-density loading. Due to the high affinity binding between catechol and boronic acid, the polymer resin readily captures boronic acid compounds. The feasibility of using immobilized catechol to capture boronic acid products for purification and solid-phase transformation was demonstrated. Moreover, the immobilized catechol was also used for the preparation of resin-bound catecholborane, which can be used as a solid-phase amidation reagent. (C) 2002 Published by Elsevier Science Ltd.

引用

页码：6339 / 6342

页数：4

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