Binding of pill from uropathogenic Escherichia coli to membranes secreted by human colonocytes and enterocytes

被引：25

作者：

Goetz, GS

Mahmood, A

Hultgren, SJ

Engle, MJ

Dodson, K

Alpers, DH

机构：

[1] Washington Univ, Sch Med, Dept Internal Med, Div Gastroenterol, St Louis, MO 63110 USA

[2] Washington Univ, Sch Med, Dept Mol Microbiol, St Louis, MO 63110 USA

来源：

INFECTION AND IMMUNITY | 1999年 / 67卷 / 11期

关键词：

D O I：

10.1128/IAI.67.11.6161-6163.1999

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

PapG adhesins mediate the binding of uropathogenic Escherichia coli. Although receptors for these adhesins have not been demonstrated in intestinal epithelia, the colonic microflora includes strains of uropathogenic E. coli. We now report that surfactant-like particles secreted by the human intestine contain receptors for PapG adhesins and may provide an intestinal habitat for uropathogenic bacteria.

引用

页码：6161 / 6163

页数：3