Prognostic Significance of Being Overweight and Obese at Diagnosis in Children With Acute Lymphoblastic Leukemia

被引：27

作者：

Aldhafiri, Fahad K. ^{[1
]}

McColl, John H. ^{[2
]}

Reilly, John J. ^{[3
]}

机构：

[1] Queen Mothers Hosp, Coll Med Vet & Life Sci, Glasgow, Lanark, Scotland

[2] Univ Glasgow, Sch Math & Stat, Glasgow, Lanark, Scotland

[3] Univ Strathclyde, Sch Psychol Sci & Hlth, Glasgow G1 1XQ, Lanark, Scotland

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2014年 / 36卷 / 03期

关键词：

acute lymphoblastic leukemia; obesity; overweight; BMI; BODY-MASS INDEX; SURVIVAL; MORTALITY;

D O I：

10.1097/MPH.0000000000000056

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

This study tested the hypothesis that being overweight/obese at diagnosis of childhood ALL was related to risk of relapse. In a national cohort of 1033 patients from the UK, there was no evidence that weight status at diagnosis was related significantly to risk of relapse: log-rank test (P=0.90) with overweight and obesity as the exposure (n=917); individual (P=0.42) and stepwise (P=0.96) proportional hazards models, with BMI Z score as the exposure. The study does not support the hypothesis that being overweight/obese at diagnosis impairs prognosis in childhood ALL in the UK.

引用

页码：234 / 236

页数：3

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