Physicochemical modelling of cell signalling pathways

被引：406

作者：

Aldridge, Bree B.

Burke, John M.

Lauffenburger, Douglas A.

Sorger, Peter K.

机构：

[1] MIT, Ctr Cell Decis Proc, Dept Biol Engn, Cambridge, MA 02139 USA

[2] Harvard Univ, Sch Med, Dept Syst Biol, Boston, MA 02115 USA

来源：

NATURE CELL BIOLOGY | 2006年 / 8卷 / 11期

关键词：

D O I：

10.1038/ncb1497

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Physicochemical modelling of signal transduction links fundamental chemical and physical principles, prior knowledge about regulatory pathways, and experimental data of various types to create powerful tools for formalizing and extending traditional molecular and cellular biology.

引用

页码：1195 / 1203

页数：9

共 45 条

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