Efficient microwave-assisted synthesis of new sulfonylbenzimidazole-4,7-diones: heterocyclic quinones with potential antitumor activity

被引：50

作者：

Boufatah, N ^{[1
]}

Gellis, A ^{[1
]}

Maldonado, J ^{[1
]}

Vanelle, P ^{[1
]}

机构：

[1] Univ Mediterranee, Fac Pharm, Lab Chim Organ Pharmaceut, CNRS,UM R6517,LCOP, F-13385 Marseille 5, France

来源：

TETRAHEDRON | 2004年 / 60卷 / 41期

关键词：

benzimidazole-4,7-diones; microwave irradiation; S-alkylation; sulfones;

D O I：

10.1016/j.tet.2004.07.070

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New benzimidazoloquinones substituted at 2-position by a sulfonyl group have been synthesized via a final microwave assisted step using 2-chloromethyl-1,5,6-trimethylbenzimidazole-4,7-dione 7 as starting material. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：9131 / 9137

页数：7

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