Catalytic asymmetric 1,4-conjugate addition of unmodified aldehyde in ionic liquid

被引：27

作者：

Hagiwara, H

Okabe, T

Hoshi, T

Suzuki, T

机构：

[1] Niigata Univ, Grad Sch Sci & Technol, Niigata 9502181, Japan

[2] Niigata Univ, Fac Engn, Niigata 9502181, Japan

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2004年 / 214卷 / 01期

关键词：

aldehyde; 1,4-conjugate addition; 5-keto-aldehyde; ionic liquid; organocatalyst;

D O I：

10.1016/j.molcata.2003.11.035

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

In the presence of a catalytic amount of optically active pyrrolidine derivatives derived from L-proline, conjugate addition of an unmodified aldehyde to 3-buten-2-one in [bmim]PF6 was achieved to afford (2S)-5-keto-aldehyde in up to 59% ee. (C) 2004 Elsevier B.V. All rights reserved.

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收藏

页码：167 / 174

页数：8

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