DBAASP: database of antimicrobial activity and structure of peptides

被引：103

作者：

Gogoladze, Giorgi ^{[1
]}

Grigolava, Maia ^{[1
]}

Vishnepolsky, Boris ^{[1
]}

Chubinidze, Mindia ^{[1
]}

Duroux, Patrice ^{[2
]}

Lefranc, Marie-Paule ^{[2
]}

Pirtskhalava, Malak ^{[1
]}

机构：

[1] Ivane Beritashvili Ctr Expt Biomed, Lab Bioinformat, GE-0160 Tbilisi, Georgia

[2] Univ Montpellier 2, IMGT, Inst Genet Humaine, Montpellier, France

来源：

FEMS MICROBIOLOGY LETTERS | 2014年 / 357卷 / 01期

基金：

美国国家科学基金会;

关键词：

antimicrobial peptide; database; antimicrobial activity; haemolytic/cytotoxic activity; PREDICTION; SEQUENCES;

D O I：

10.1111/1574-6968.12489

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学];

摘要：

The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is a manually curated database for those peptides for which antimicrobial activity against particular targets has been evaluated experimentally. The database is a depository of complete information on: the chemical structure of peptides; target species; target object of cell; peptide antimicrobial/haemolytic/cytotoxic activities; and experimental conditions at which activities were estimated. The DBAASP search page allows the user to search peptides according to their structural characteristics, complexity type (monomer, dimer and two-peptide), source, synthesis type (ribosomal, nonribosomal and synthetic) and target species. The database prediction algorithm provides a tool for rational design of new antimicrobial peptides. DBAASP is accessible at http://www.biomedicine.org.ge/dbaasp/.

引用

页码：63 / 68

页数：6

共 19 条

[1]

Antimicrobial peptides: Pore formers or metabolic inhibitors in bacteria? [J].

Brogden, KA .

NATURE REVIEWS MICROBIOLOGY, 2005, 3 (03) :238-250

[2]

NORINE:: a database of nonribosomal peptides [J].

Caboche, Segolene ;

Pupin, Maude ;

Leclere, Valerie ;

Fontaine, Arnaud ;

Jacques, Philippe ;

Kucherov, Gregory .

NUCLEIC ACIDS RESEARCH, 2008, 36 :D326-D331

[3]

Diversity of Monomers in Nonribosomal Peptides: towards the Prediction of Origin and Biological Activity [J].

Caboche, Segolene ;

Leclere, Valerie ;

Pupin, Maude ;

Kucherov, Gregory ;

Jacques, Philippe .

JOURNAL OF BACTERIOLOGY, 2010, 192 (19) :5143-5150

[4]

Only six kingdoms of life [J].

Cavalier-Smith, T .

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2004, 271 (1545) :1251-1262

[5]

Giudicelli Veronique, 2012, Frontiers in Genetics, V3, P79, DOI 10.3389/fgene.2012.00079

[6]

PenBase, the shrimp antimicrobial peptide penaeidin database:: Sequence-based classification and recommended nomenclature [J].

Gueguen, Y ;

Garnier, J ;

Robert, L ;

Lefranc, MP ;

Mougenot, I ;

de Lorgeril, J ;

Janech, M ;

Gross, PS ;

Warr, GW ;

Cuthbertson, B ;

Barracco, MA ;

Bulet, P ;

Aumelas, A ;

Yang, YS ;

Bo, D ;

Xiang, JH ;

Tassanakajon, A ;

Piquemal, D ;

Bachère, E .

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2006, 30 (03) :283-288

[7]

BACTIBASE: a new web-accessible database for bacteriocin characterization [J].

Hammami, Riadh ;

Zouhir, Abdelmajid ;

Ben Hamida, Jeannette ;

Fliss, Ismail .

BMC MICROBIOLOGY, 2007, 7 (1)

[8]

PhytAMP: a database dedicated to antimicrobial plant peptides [J].

Hammami, Riadh ;

Ben Hamida, Jeannette ;

Vergoten, Grard ;

Fliss, Ismail .

NUCLEIC ACIDS RESEARCH, 2009, 37 :D963-D968

[9]

RAPD: a database of recombinantly-produced antimicrobial peptides [J].

Li, Yifeng ;

Chen, Zhengxin .

FEMS MICROBIOLOGY LETTERS, 2008, 289 (02) :126-129

[10]

DADP: the database of anuran defense peptides [J].

Novkovic, Mario ;

Simunic, Juraj ;

Bojovic, Viktor ;

Tossi, Alessandro ;

Juretic, Davor .

BIOINFORMATICS, 2012, 28 (10) :1406-1407

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