A chromosome RNAissance

被引：43

作者：

Dernburg, AF

Karpen, GH

机构：

[1] Univ Calif Berkeley, Lawrence Berkeley Lab, Div Life Sci, Berkeley, CA 94720 USA

[2] Salk Inst Biol Studies, MCBL, La Jolla, CA 92037 USA

来源：

CELL | 2002年 / 111卷 / 02期

关键词：

D O I：

10.1016/S0092-8674(02)01039-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In RNA-mediated interference (RNAI), double-stranded RNAs (dsRNAs) target complementary mRNAs for degradation. New work demonstrates that essential chromosomal functions are mediated through RNAi protein components and short RNAs, which alter chromosome function at specific DNA loci via histone modification.

引用

页码：159 / 162

页数：4

共 17 条

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