The effects of specific nutrients on the regulation of feeding behaviour in human subjects

被引:14
作者
French, SJ [1 ]
机构
[1] Univ Sheffield, No Gen Hosp, Ctr Human Nutr, Sheffield S5 7AU, S Yorkshire, England
关键词
appetite; gastrointestinal function; macronutrients;
D O I
10.1017/S0029665199000701
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Regulation of short-term energy intake involves the balance of positive drives to eat arising from the sight, smell and palatability of food with negative feedback signals from learned associations, gastrointestinal and metabolic signals. The stomach and small intestine are major sites in the feedback inhibition of food intake and subsequent period of appetite suppression. The present paper reviews the evidence that not only does the nature of the regulatory signal suppressing food intake depend on the type and energy content of nutrient consumed, but also the specific chemical composition of the nutrients and the site at which they are delivered. It is evident that feedback inhibition of feeding can be modulated by the particular chemical structure of nutrients (e.g. specific sugar or triacylglycerol structures). These differences in response are likely to be a consequence of differences in physical properties of particular nutrients depending on their chemical structure, and may also result from different receptor affinities for specific dietary structures. Moreover, the site of administration of nutrients can also profoundly affect the size and nature of the subsequent feeding response, suggesting that feed-forward interactions occur between the taste of foods and gastrointestinal stimulation.
引用
收藏
页码:533 / 539
页数:7
相关论文
共 66 条
[61]   Dietary fat and obesity: an epidemiologic perspective [J].
Seidell, JC .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1998, 67 (03) :546S-550S
[62]   ACCURATE ENERGY COMPENSATION FOR INTRAGASTRIC AND ORAL NUTRIENTS IN LEAN MALES [J].
SHIDE, DJ ;
CABALLERO, B ;
REIDELBERGER, R ;
ROLLS, BJ .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1995, 61 (04) :754-764
[63]   THE EFFECTS OF GLYCERIDE STRUCTURE ON ABSORPTION AND METABOLISM [J].
SMALL, DM .
ANNUAL REVIEW OF NUTRITION, 1991, 11 :413-434
[64]   EFFECTS OF FRUCTOSE AND GLUCOSE PRELOADS ON SUBSEQUENT FOOD-INTAKE [J].
SPITZER, L ;
RODIN, J .
APPETITE, 1987, 8 (02) :135-145
[65]   Oral sensory stimulation improves glucose tolerance in humans: Effects on insulin, C-peptide, and glucagon [J].
Teff, KL ;
Engelman, K .
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 1996, 270 (06) :R1371-R1379
[66]   Is dietary fat a major determinant of body fat? [J].
Willett, WC .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1998, 67 (03) :556S-562S