Ordered mesoporous materials in the context of drug delivery systems and bone tissue engineering

被引：424

作者：

Vallet-Regi, Maria ^{[1
]}

机构：

[1] UCM, Fac Farm, Dept Quim Inorgan & Bioinorgan, Madrid 28040, Spain

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2006年 / 12卷 / 23期

关键词：

bioceramics; bone tissue regeneration; drug delivery; mesoporous materials;

D O I：

10.1002/chem.200600226

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chemistry, materials science and medicine are research areas that converge in the field of drug delivery systems and tissue engineering. This paper tries to introduce an example of such an interaction, aimed at solving health issues within the world of biomaterials. Ordered mesoporous materials can be loaded with different organic molecules that would be released afterwards, in a controlled fashion, inside a living body. These materials can also react with the body fluids giving rise to carbonated nanoapatite particles as the products of such a chemical interaction; these particles, equivalent to biological apatites, enable the regeneration of bone tissue.

引用

页码：5934 / 5943

页数：10

共 84 条

[1]

Aiello R, 2002, STUD SURF SCI CATAL, V142, P1165

[2] Influences of material characteristics on ibuprofen drug loading and release profiles from ordered micro- and mesoporous silica matrices [J].

Andersson, J ;

Rosenholm, J ;

Areva, S ;

Lindén, M .

CHEMISTRY OF MATERIALS, 2004, 16 (21) :4160-4167

[3]

ARIGA K, 2005, HDB NANOSTRUCTURED B, V1, P343

[4] Solid state NMR characterisation of encapsulated molecules in mesoporous silica [J].

Babonneau, F ;

Yeung, L ;

Steunou, N ;

Gervais, C ;

Ramila, A ;

Vallet-Regi, M .

JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, 2004, 31 (1-3) :219-223

[5]

Babonneau F, 2003, MATER RES SOC SYMP P, V775, P77

[6]

BECK J, 1991, Patent No. 9111390

[7] A NEW FAMILY OF MESOPOROUS MOLECULAR-SIEVES PREPARED WITH LIQUID-CRYSTAL TEMPLATES [J].

BECK, JS ;

VARTULI, JC ;

ROTH, WJ ;

LEONOWICZ, ME ;

KRESGE, CT ;

SCHMITT, KD ;

CHU, CTW ;

OLSON, DH ;

SHEPPARD, EW ;

MCCULLEN, SB ;

HIGGINS, JB ;

SCHLENKER, JL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (27) :10834-10843

[8] Preparation and characterization of siliceous material using liposomes as template [J].

Bégu, S ;

Durand, R ;

Lerner, DA ;

Charnay, C ;

Tourné-Péteilh, C ;

Devoisselle, JM .

CHEMICAL COMMUNICATIONS, 2003, (05) :640-641

[9] Influence of alkyl peptidoamines on the structure of functionalized mesoporous silica [J].

Blin, JL ;

Gérardin, C ;

Rodehüser, L ;

Selve, C ;

Stébé, MJ .

CHEMISTRY OF MATERIALS, 2004, 16 (24) :5071-5080

[10]

Blin JL, 2005, STUD SURF SCI CATAL, V156, P221

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