Intramolecular cycloadditions of α-allyloxycarbonylnitrones:: Stereoselective synthesis of 3-amino-2(5H)furanones

被引：22

作者：

Chiacchio, U

Corsaro, A

Iannazzo, D

Piperno, A

Procopio, A

Rescifina, A

Romeo, G

Romeo, R

机构：

[1] Univ Catania, Dipartimento Sci Chim, I-95125 Catania, Italy

[2] Univ Messina, Dipartimento Farmacochim, I-98168 Messina, Italy

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 12期

关键词：

D O I：

10.1021/jo025626h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of furoisoxazolidines with NaH leads to functionalized 3-amino-2(5H)-furanones through a new rearrangement pattern of the isoxazolidine nucleus. This process has been usefully exploited for the synthesis of enantiomerically pure (5R)-3-alkylamino-5-methyl-2(5H)-furanones.

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页码：4380 / 4383

页数：4

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