Biotechnological production of 2-phenylethanol

被引：410

作者：

Etschmann, MMW

Bluemke, W

Sell, D

Schrader, J

机构：

[1] Dechema EV, Biochem Engn Grp, D-60486 Frankfurt, Germany

[2] GKSS Forschungszentrum Geesthacht GmbH, Inst Chem, D-21502 Geesthacht, Germany

来源：

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 2002年 / 59卷 / 01期

关键词：

D O I：

10.1007/s00253-002-0992-x

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

2-Phenylethanol (2-PE) is an important flavour and fragrance compound with a rose-like odour. Most of the world's annual production of several thousand tons is synthesised by chemical means but, due to increasing demand for natural flavours, alternative production methods are being sought. Harnessing the Ehrlich pathway of yeasts by bioconversion Of L-phenylalanine to 2-PE could be an option, but in situ product removal is necessary due to product inhibition. This review describes the microbial production of 2-PE, and also summarizes the chemical syntheses and the market situation.

引用

页码：1 / 8

页数：8

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[1] MUTANTS OF SACCHAROMYCES-CEREVISIAE PRODUCING A LARGE QUANTITY OF BETA-PHENETHYL ALCOHOL AND BETA-PHENETHYL ACETATE [J].