Scaffolded DNA Origami of a DNA Tetrahedron Molecular Container

被引：268

作者：

Ke, Yonggang ^{[1
,2
]}

Sharma, Jaswinder ^{[1
,2
]}

Liu, Minghui ^{[1
,2
]}

Jahn, Kasper ^{[3
]}

Liu, Yan ^{[1
,2
]}

Yan, Hao ^{[1
,2
]}

机构：

[1] Arizona State Univ, Dept Chem & Biochem, Tempe, AZ 85287 USA

[2] Arizona State Univ, Biodesign Inst, Tempe, AZ 85287 USA

[3] Aarhus Univ, Ctr DNA Nanotechnol & iNANO, DK-8000 Aarhus, Denmark

来源：

NANO LETTERS | 2009年 / 9卷 / 06期

关键词：

OCTAHEDRON;

D O I：

10.1021/nl901165f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We describe a strategy of scaffolded DNA origami to design and construct 3D molecular cages of tetrahedron geometry with inside volume closed by triangular faces. Each edge of the triangular face is similar to 54 nm in dimension. The estimated total external volume and the internal cavity of the triangular pyramid are about 1.8 x 10(-23) and 1.5 x 10(-23) m(3), respectively. Correct formation of the tetrahedron DNA cage was verified by gel electrophoresis, atomic force microscopy, transmission electron microscopy, and dynamic light scattering techniques.

引用

页码：2445 / 2447

页数：3

共 14 条

[1] Assembling materials with DNA as the guide [J].

Aldaye, Faisal A. ;

Palmer, Alison L. ;

Sleiman, Hanadi F. .

SCIENCE, 2008, 321 (5897) :1795-1799

[2] Modular access to structurally switchable 3D discrete DNA assemblies [J].

Aldaye, Faisal A. ;

Sleiman, Hanadi F. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (44) :13376-+

[3]

Bhatia D.Bhatia, 2009, ANGEW CHEM, V121, P4198, DOI DOI 10.1002/ANGE.200806000

[4] SYNTHESIS FROM DNA OF A MOLECULE WITH THE CONNECTIVITY OF A CUBE [J].

CHEN, JH ;

SEEMAN, NC .

NATURE, 1991, 350 (6319) :631-633

[5] A self-assembled DNA bipyramid [J].

Erben, Christoph M. ;

Goodman, Russell P. ;

Turberfield, Andrew J. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (22) :6992-+

[6] The I-Tetraplex building block: Rational design and controlled fabrication of robust 1D DNA scaffolds through non-Watson-Crick interactions [J].

Ghodke, Harshad B. ;

Krishnan, Ramya ;

Vignesh, Kasinath ;

Kumar, G. V. Pavan ;

Narayana, Chandrabhas ;

Krishnan, Yamuna .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (15) :2646-2649

[7] Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication [J].

Goodman, RP ;

Schaap, IAT ;

Tardin, CF ;

Erben, CM ;

Berry, RM ;

Schmidt, CF ;

Turberfield, AJ .

SCIENCE, 2005, 310 (5754) :1661-1665

[8] Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra [J].

He, Yu ;

Ye, Tao ;

Su, Min ;

Zhang, Chuan ;

Ribbe, Alexander E. ;

Jiang, Wen ;

Mao, Chengde .

NATURE, 2008, 452 (7184) :198-U41

[9] Designer DNA Nanoarchitectures [J].

Lin, Chenxiang ;

Liu, Yan ;

Yan, Hao .

BIOCHEMISTRY, 2009, 48 (08) :1663-1674

[10] Pyramidal and Chiral Groupings of Gold Nanocrystals Assembled Using DNA Scaffolds [J].

Mastroianni, Alexander J. ;

Claridge, Shelley A. ;

Alivisatos, A. Paul .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (24) :8455-8459

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