The I-Tetraplex building block: Rational design and controlled fabrication of robust 1D DNA scaffolds through non-Watson-Crick interactions

被引：41

作者：

Ghodke, Harshad B.

Krishnan, Ramya

Vignesh, Kasinath

Kumar, G. V. Pavan

Narayana, Chandrabhas

Krishnan, Yamuna

机构：

[1] TIFR, Natl Ctr Biol Sci, Bangalore 560065, Karnataka, India

[2] Jawaharlal Nehru Ctr Adv Sci Res, Chem & Phys Mat Unit, Light Scattering Lab, Bangalore 560064, Karnataka, India

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2007年 / 46卷 / 15期

关键词：

DNA; i motif; nanostructures; scanning probe microscopy; self-assembly;

D O I：

10.1002/anie.200604461

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) All wired up: Robust 1D scaffolds have been designed based on the i tetraplex by a strategy of inducing bidirectional growth on "slipped" tetraplexes. The growth propagates through non-Watson-Crick base-pairing and leads to nanowires more than 3 μm long. These nanowires have been characterized by microscopy (AFM and TEM, see picture), surface-enhanced Raman spectroscopy, and circular dichroism spectroscopy. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2646 / 2649

页数：4

共 29 条

[1] Raman signature of the four-stranded intercalated cytosine motif in crystal and solution structures of DNA deoxycytidylates d(CCCT) and d(C-8) [J].