Nucleoplasmin:: a nuclear chaperone

被引：41

作者：

Prado, A

Ramos, I

Frehlick, LJ

Muga, A

Ausió, J

机构：

[1] Univ Basque Country, CSIC, Unidad Biofis, Bilbao 48080, Spain

[2] Univ Victoria, Dept Biochem & Microbiol, Victoria, BC V8W 3P6, Canada

来源：

BIOCHEMISTRY AND CELL BIOLOGY | 2004年 / 82卷 / 04期

关键词：

nucleoplasmin; review; histone chaperone; sperm chromatin remodeling; nucleosome assembly;

D O I：

10.1139/O04-042

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this article, we briefly review the structural and functional information currently available on nucleoplasmin. Special emphasis is placed on the discussion of the molecular mechanism involved in the sperm chromatin remodelling activity of this protein. A model is proposed based on current crystallographic data, recent biophysical and functional studies, as well as in the previously available information.

引用

页码：437 / 445

页数：9

共 68 条

[31] NUCLEOSOME ASSEMBLY INVITRO - SEPARATE HISTONE TRANSFER AND SYNERGISTIC INTERACTION OF NATIVE HISTONE COMPLEXES PURIFIED FROM NUCLEI OF XENOPUS-LAEVIS OOCYTES [J].