DNA designer defects in photonic crystals: Optically monitored biochemistry

被引:43
作者
Fleischhaker, Friederike
Arsenault, Andre C.
Peiris, Frank C.
Kitaev, Vladimir
Manners, Ian
Zentel, Rudolf
Ozin, Geoffrey A.
机构
[1] Univ Toronto, Dept Chem, Mat Chem Res Grp, Toronto, ON M5S 3H6, Canada
[2] Johannes Gutenberg Univ Mainz, Inst Organ Chem, Dept Chem & Pharm, D-55128 Mainz, Germany
关键词
D O I
10.1002/adma.200600579
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Biomolecules have been incorporated as designed planar defect layers in colloidal photonic crystals using self- assembly techniques (see figure). Through shifts of the photonic intragap defect mode, for example, DNA conformational changes and the enantioselective intercalation of a chiral anticancer drug can be optically monitored. This newfound capability for optically monitoring biochemistry bodes well for the development of a new generation of simple on-the-spot color readout biosensors.
引用
收藏
页码:2387 / +
页数:6
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