Cancer diagnosis by autofluorescence of blood components

被引：90

作者：

Masilamani, V

Al-Zhrani, K

Al-Salhi, M

Al-Diab, A

Al-Ageily, M

机构：

[1] King Saud Univ, Dept Phys, Laser Grp, Coll Sci, Riyadh 1145, Saudi Arabia

[2] King Khalid Univ Hosp, Div Oncol, Coll Med, Riyadh 11472, Saudi Arabia

[3] Riyadh Cent Hosp, Riyadh, Saudi Arabia

来源：

JOURNAL OF LUMINESCENCE | 2004年 / 109卷 / 3-4期

关键词：

autofluorescence of blood components; diagnosis of cancer; porphyrin; cancer marker; spectral signatures of cancer;

D O I：

10.1016/j.jlumin.2004.02.001

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

The autofluorescence of blood components of healthy volunteers and cancer patients of different etiology were analyzed using a steady-state spectrofluorometer. A significant contrast between healthy and diseased blood could be established. Blood components of patients of gastric cancer, breast cancer and Hodgkin's lymphoma showed distinct and enhanced fluorescence band (around 630 nm) due to the porphyrin fluorophore. From the ratio fluorometry, a correlation to the stages of cancer could be also brought forth. We could indicate reasonably well the features of early stages and the growth rate of a few cancers and benign tumors. (C) 2004 Published by Elsevier B.V.

引用

页码：143 / 154

页数：12

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