Formation of enamides via palladium(II)-catalyzed vinyl transfer from vinyl ethers to nitrogen nucleophiles

被引:96
作者
Brice, JL [1 ]
Meerdink, JE [1 ]
Stahl, SS [1 ]
机构
[1] Univ Wisconsin, Madison, WI 53706 USA
关键词
D O I
10.1021/ol0494360
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Palladium(II) complexes catalyze the formation of enamides via the formal cross-coupling reaction between nitrogen nucleophiles and vinyl ethers. These vinyl transfer reactions proceed in good yields with amide, carbamate, and sulfonamide nucleophiles, and the optimal catalyst is (DPP)Pd(OCOCF3)(2) (DPP = 4,7-diphenyl-1,10-phenanthroline).
引用
收藏
页码:1845 / 1848
页数:4
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