Formation of enamides via palladium(II)-catalyzed vinyl transfer from vinyl ethers to nitrogen nucleophiles

被引：96

作者：

Brice, JL ^{[1
]}

Meerdink, JE ^{[1
]}

Stahl, SS ^{[1
]}

机构：

[1] Univ Wisconsin, Madison, WI 53706 USA

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 11期

关键词：

D O I：

10.1021/ol0494360

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium(II) complexes catalyze the formation of enamides via the formal cross-coupling reaction between nitrogen nucleophiles and vinyl ethers. These vinyl transfer reactions proceed in good yields with amide, carbamate, and sulfonamide nucleophiles, and the optimal catalyst is (DPP)Pd(OCOCF3)(2) (DPP = 4,7-diphenyl-1,10-phenanthroline).

引用

页码：1845 / 1848

页数：4

共 65 条

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